Methotrexate-induced mucositis with extra-mucosal involvement after acidental overdose

Methotrexate-induced mucositis with extra-mucosal involvement after acidental overdose*

leiomyosarcoma.2 The extremities are the most common sites of involvement, especially the lower limbs. However, any area of the body can be affected, and approximately 10-15% are located in the tissue of the head and neck.5 For diagnosis, histopathology study associated to the immunohistochemistry are necessary.5 The basis of treatment is total surgical resection of the tumor with wide safety m...

Accidental intrathecal methotrexate overdose.

Methotrexate induced mucosal erosions and ulcerations

The patient reported that his mouth and throat were painful and he had difficulty in swallowing food. Initially, the ulcers had persisted over the two weeks following the prescription of Dynexan®, Augmentin 1g BDS for 5 days, Andolex C® and Mucain mouthwash®, by his general practitioner. Subsequent referral to an ENT surgeon had resulted in confirmation of an extra-oesophageal reflux component....

Preventing deaths from methotrexate overdose.

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Lip Leishmaniasis with Oral-mucosal Involvement: A Case Report

Statement of the problem: Nowadays leishmaniasis is a common infectious disease around the world which is caused by a protozoan parasite named Leishmania. This parasite is transmitted to human by an infected female sand fly. This disease has three clinical forms; mucosal forms are rare in Iran. Purpose: The purpose of this study was to report a case of leishmaniasis with lip and oral mucosal in...